因为她与梅葛一世的婚姻，雷妮亚被称作梅葛的“黑新娘”。在杰赫里斯一世统治时代，她在仙女岛寓居时代被称作“Queen in the West”，在龙石岛寓居时代被称作“Queen in the East”。
Following Maegor's death, discussion arose as to who had the better claim to the Iron Throne. There were some who suggested that Rhaena's claim, as the firstborn child of King Aenys I Targaryen and Queen Alyssa Velaryon, was the strongest. Her gender argued against her, however, and Rhaena herself had come to loathe King's Landing and its court. The claims of her daughters were argued for as well. If Maegor was to be considered a usurper, the true king would have been Rhaena's husband, Aegon, who had claimed the throne before Jaehaerys had. As such, some suggested the throne should pass to one of his daughters by Rhaena, Aerea and Rhaella. The girls did not have much support, however, and Rhaena herself agreed that the crown should go to Jaehaerys instead.
In late 48AC, Rhaena traveled to Oldtown with the court for the coronation of Jaehaerys in the Starry Sept by the High Septon. Nine days later, Jaehaerys departed Oldtown for King's Landing with Rhaena's elder daughter Aerea, whilst her younger daughter Rhaella remained in Oldtown. At the time, it was widely believed that someone had switched Rhaena's twin daughters, disguising Aerea as Rhaella and Rhaella as Aerea. Archmaester Gyldayn has suggested both Rhaena and her mother, Dowager Queen Alyssa Velaryon, as the person responsible for the switch.